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UICC World Cancer Congress 2006
Bridging the Gap: Transforming Knowledge into Action
July 8-12, 2006, Washington, DC, USA
Methods:Fifty patients with ovarian tumors requiring operative intervention entered the study prospectively underwent pelvic examination, tumor marker assessment and gray-scale transvaginal 6.5MHz transducer and extended transabdominally when needed with 3.5 MHz transducer, with color flow Doppler ultrasonography preoperatively. Risk of malignancy index, Sassone scoring were calculated respectively. Histopathology was taken as gold standard to compare the preoperative diagnosis.
Results:Out of 50 patients presented with ovarian tumors, 20 (40%) had malignant disease and 30 (60%) benign pathology. CA 125 tumor marker had sensitivity of 78% and specificity of 75%, risk of malignancy index had sensitivity of 86.67 %, specificity of 92.5 %. Ultrasound (Sassone scoring) had highest specificity of 93% and Doppler had highest sensitivity of 100%. All the above indices should be used together for appropriate diagnosis and management of ovarian neoplasm.