UICC World Cancer Congress 2006

Objective: Specific gravity of lung cancer (LC) within the framework of oncological incidence in RF is 22.8% for male and 4.0% for female; in Altai region - 28.2% and 4.8%, respectively. LC headlines the list of death rates from malignancies with male, and is the fourth in the list with female. Methods: Medical prevention of LC included general and individual measures. It implied carrying out organizing and methodological arrangement and medical and health-managing control. The algorithm of forming of high-risk groups for LC included defining cohorts of individuals having risk factors and their interviewing. According to the number of risks factors individuals were defined into groups of 'increased' risk or 'high' risk. Patients of the increased-risk group were under monitoring of general practitioners (with checking up once per 3 year). Patients of the high-risk group (having unhealthy conditions of work, family history of LC, subjected to radioactive exposures) were under monitoring of oncologists and were annually thoroughly examined (including CT, NMRT, bronchoscopy, oncomarkers, etc). Results: 2813 patients were included into the pre-cancer high-risk registry. In 2004-2005 64 cases of malignancies were diagnosed (including 6 [0.25%] cases of LC). All malignancies (100%) were revealed in early stages, while among all new cases of LC revealed in Altai region in 2004 specific gravity of early stages were 42.7%. Conclusion: The forming of groups of increased and high risk of LC makes it possible to select individuals for the risk groups. It makes preventive measures more specifically oriented and the search for early cancers more effective.