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UICC World Cancer Congress 2006

Bridging the Gap: Transforming Knowledge into Action

July 8-12, 2006, Washington, DC, USA

Monday, 10 July 2006 - 1:30 PM
94-1

Evidence-Based Guidelines for Lung Cancer Diagnosis and Treatment

W. Michael Alberts, MD, FCCP, H. Lee Moffitt Cancer Center, 12902 Magnolia Drive, Tampa, FL 33612-9416, James R. Jett, MD, FCCP, Department of Medicine, Mayo Medical School, 200 FIrst St. SW, Desk E18B, Rochester, MN 55905, Gene L. Colice, MD, FCCP, Critical Care and Respiratory Services, Washington Hospital Center, 110 Irving St. NW, Washington, DC 20010, Lary Robinson, MD, FCCP, Surgery, H. Lee Moffitt Cancer Center, 12902 Magnolia Drive, Tampa, FL 33612-9416, and Frank Detterbeck, MD, FCCP, Surgery, Yale University, FMB 128, 333 Cedar St., New Haven, CT 06520.

Objective: The American College of Chest Physicians (ACCP) has developed evidence-based lung cancer guidelines that synthesize the published literature and provide recommendations to assist physicians in achieving the best possible patient outcomes.

Lung cancer is currently the leading cause of cancer deaths in both men and women in the United States, causing more deaths (163,150) than the next four most common cancers combined (colon - 56,290, breast - 40,870, and prostate - 31,800, pancreas - 30,350). Worldwide, approximately one to two million people die of this disease each year. The expected 5-year survival for all patients diagnosed with lung cancer is 15%. Little progress has been made in the successful treatment of this disease as the 5 year survival was 13% in 1974. A number of promising new diagnostic and treatment modalities, however, have been introduced that may offer potential improvements in survival.

Methods: The ACCP commissioned a review of existing lung cancer guidelines, systematic reviews and meta-analyses, and primary studies of designated topic areas. Evidence tables were produced and used to develop the guideline recommendations. The writing panel was an international group of over 80 lung cancer experts, representing seven specialties and thirteen medical, nursing, and patient advocacy associations.

Results: The guidelines were published in CHEST 2003; 123(1 suppl): 1s-337s, providing recommendations for screening, diagnosis and treatment of lung cancer. This session will review the treatment recommendations for non small cell and small cell lung cancer.


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