UICC World Cancer Congress 2006

Objective: To develop a functional international panel of cancer experts to participate in TNM review and improvement process; and review its formation, membership engagement and success. Methods: In 2001 the UICC TNM Committee invited a multidisciplinary cadre of experts in major disease sites representing diverse geographic regions to assist in judging current status and new developments in the TNM classification. Criteria for invitation included: recognition for expertise, position as respected opinion leader, interest in staging issues, strong publication record, agreement to serve for at least three years, and willingness to work on-line via e-mail. The TNM Process Task Force members performed a structured literature search, triaging annually, with selected literature sent to Panel members for review. Feedback was obtained via brief questionnaire. Results: Between 2001-2004, Expert Panels comprised 85 members from 15 countries representing six disciplines: surgery, pathology, internal medicine, medical and radiation oncology, and epidemiology. Panel sites included breast(6) gastrointestinal(18), genitourinary(10), gynecology(8), head and neck(10), lung(9), lymphoma(8), sarcoma/ bone(8) and skin(9). Each consecutive year from 2002 the literature watch process selected 21/141, 37/189 and 59/436 articles for review. Overall response rates were 74%, 70%, and 50% increasing to 82% in 2005. 84% of panel members accepted re-appointment in 2005, with 17 new members added. Future aims are to expand representation from South America, Asia and Eastern Europe, improve the Literature Watch process, and disseminate feedback to Panel members. Panel Members will be integral to the promotion of TNM use, worldwide engagement of the oncology community, and improved quality of the TNM classification.