The 13th World Conference on Tobacco OR Health

Objective: Environmental Tobacco Smoke ETS is a main source of exposure to many toxic substances in indoor microenvironments. There are some models available that allow analysis of such exposure but most of them are very complicated. On the other hand, exposure to toxic substances from ETS is very rarely quantified.

Methods: The new software was developed that allows simulation, analysis and quantification of exposure to toxic substances from ETS. The ExPaS software (Exposure of Passive Smokers) is based on simple prognostic equations that simulate distribution of toxic agents concentration in indoor microenvironment. The following inputs are required to perform simulation with ExPaS: number of smokers present in a room, a frequency of smoked cigarettes, time of exposure during a day, time of exposure during a lifetime, room volume, air ventilation coefficient, levels of analyzed toxic compound in MS and SS and its retention in smoker's lungs. ExPaS simulator has its own database that contains information about levels of various toxic substances in MS and SS of many commercially sold cigarettes and their lung retention. Quantification of exposure to carcinogens is performed with ExPaS-C module based on an air unit risk and to non-carcinogens with ExPaS-NC module based on a reference concentration.

Results: A mean concentration of toxic compound in indoor air and the percentage of its reference concentration will be calculated with ExPaS software. The distribution of toxic agent concentration during exposure will be visualized. A risk of cancer development will be calculated for carcinogenic constituents of ETS.