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The 13th World Conference on Tobacco OR Health

Building capacity for a tobacco-free world

July 12-15, 2006, Washington, DC, USA



Thursday, July 13, 2006 - 12:00 PM
13-301

Validation of self reported smoking by urinary cotinine measurement in a women hospital staff in Tunisia

RADHOUANE FAKHFAKH, MD1, A. KLOUZ2, W. BOUJOMAA3, F BEN SALAH3, R GHARBI3, M. Lakhal4, C. BELKHIA4, and N. ACHOUR1. (1) HEALTH EDUCATION, INSTITUT NATIONAL DE SANTE PUBLIQUE, 5-7 RUE KHARTOUM IMM LE DIPLOMAT 1002 LE BELVEDERE TUNIS, TUNIS, Tunisia, (2) CENTRE NATIONAL DE PHARMACO-VIGILANCE TUNIS, (3) HEALTH OCCUPATION, HOPITAL CHARLES NICOLLE, RUE 9 AVRIL, Tunisia, (4) centre national de pharmacovigilance

Objective: The validity of self reported smoking in population surveys remains an important question .This has been of particular concern in a situation where there is a strong social pressure against smoking like in hospital staff in particular among women in Tunisian socio-cultural context. An associated question is what would be the value of measuring urinary cotinine concentrations in such surveys to obtain validated smoking data.

Methods: Cross sectional analysis of data on self reported smoking and urinary cotinine among a sample of 809 women Charles Nicolles hospital, who participated in the hospital staff tobacco use survey. We used quantitative colorimetric urine test based on the könig reaction, in which pink-red chromophores formed from nicotine and its metabolites condensation with barbituric acid were extracted into acetate buffer.

Results: Among self reported women hospital staff regular smokers, 72.7% had a cotinine concentration of cutt off 7,6 micromol/ml or higher in urine. Of those participants who reported to smoked occasionally 14,3% of women had a cotinine concentration in urine at least 7,6 micromol/ml. Among reported ex- smokers and never smoking, respectively 10,9% and 14,8% of women had cotinine in their urine at cutt-off level. The validity of self reporting was similar among subjects from different areas, ages, and professional categories groups. Conclusions: These results substantiate the unreliability of self-report on smoking status in women hospital staff in Tunisia and have implications for clinical and education practice