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The 13th World Conference on Tobacco OR Health
Building capacity for a tobacco-free world
July 12-15, 2006, Washington, DC, USA
Objective: The relationship between maternal and spouses' expired air CO concentrations (EACO) on fetal growth has not yet been evaluated.
Methods: 856 smoking and nonsmoking pregnant women were followed during their pregnancy. Their EACO was determined in the first trimester and during delivery. The spouses' EACO were also measured at delivery. The main outcome measures was the infants' birth weight. Secondary measures included head circumference, Apgar score and heart rate at delivery. Cord blood fetal carboxyhemoglobin (FCOHb) served as internal control.
Results: Birth weight dose-dependently and significantly decreased with increasing level of maternal (0-5: 3406 ; 32; 6-10: 3048 „b 57; 11-20: 2858 ; 54; >20 ppm: 2739 ; 34 g (p<0.0001) or spouses' EACO (0-5: 3546 ; 25; 6-10: 3484 ; 51; 11-20: 3309 47; >20 ppm: 3190 ; 57 g, p<0.0001). Even the birth weight of newborns whose mother had EACO between 6 and 10 ppm was significantly lower than the birth weight of newborns whose mother had an EACO between 0 and 5 ppm. Spouses' EACO of delivering women with EACO of 0-5 ppm showed similar effect.