The 13th World Conference on Tobacco OR Health

Objective:

A multi centre study to measure the relative risk (RR) of Lung Cancer in life time non smokers connected with Environmental Tobacco Smoke (ETS) exposure.

Methods:

Six cities in Nigeria were considered; Lagos, Ibadan, Kano, Akure, Benin and Asaba. Female life time never smokers: 653 cases with histological confirmed lung cancer and 1200 controls selected by random digit dialing and random sampling from the ministry of health files from each state for women aged 61 years and above.

Results: The relative risk of Lung Cancer, estimated by adjusted odds ratio or with 95% confidence interval (CI) associated with a 30% excess risk of lung cancer. All types of primary lung carcinoma (adjusted or =1.29: < 05). Pulmonary adencarcinoma (adjusted or 1.37: p =18).

An increasing relative risk of Lung Cancer was observed with increasing pack-years of spousal ETS exposure (trend p= 0.3), such that an 80% exposure excess risk of Lung Cancer was observed for subjects with 80 or more pack-years of exposure form a spouse (adjusted or 1.78 : 95% CI = 0.99 to 3.25). The excess risk of Lung Cancer among women exposed to ETS during adult life on the household was 24% in the work place, 39% and in social gathering, 50% when this sources were considered jointly, an increasing risk of Lung Cancer with Increasing duration of exposure was observed (trend p =001). At the highest level of exposure during childhood to childhood ETS exposure for mother, father, or other household members.