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The 13th World Conference on Tobacco OR Health

Building capacity for a tobacco-free world

July 12-15, 2006, Washington, DC, USA

Thursday, July 13, 2006 - 12:00 PM

Characteristics and salivary cotinine level among smokers of cigarettes with descriptors light and regular in a pooled study population of Brazil, Poland, China and Mexico

Valeska Figueiredo, MD, MPH, Prevention and Surveillance Coordination/Epidemiology Division, National Cancer Institute of Brazil, Rua dos Invalidos, 212/ 3ºfloor, Rio de Janeiro, Brazil, Moysez Szklo, MD, MPH, PhD, Department of Epidemiology, Johns Hopkins Bloomber School of Public Health, 615 North Wolfe Street, Room W6010, MD 21205, Amanda Blackford, MPH, Division of Biostatistics, Department of Oncology, Johns Hopkins School of Medicine, Baltimore, MD, Krzysztof Przewozniak, The Maria Sklodowska-Curie Memorial Cancer Center, Warsaw, Poland, Neal Benowitz, MD, Division of Clinical Pharmacology and Experimental Therapeutics, Departments of Medicine and Biopharmaceutical Sciences, University of California, Gonghuan Yang, MD, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences, Beijin, China, and Mauricio Hernandez-Avila, PhD, General Direction, National Institute of Public Health, Av. Universidad 655, Col. Sta. Maria Ahuacatitlán, Cuernavaca, 62508, Mexico.

Objective: After effective tobacco control measures adopted by developed countries, tobacco industry increased investments on developing country markets. The use of “light” descriptors in cigarette packs is one of industry strategies to increase tobacco consumption. The objective of this study is to describe the differences between smokers of “light” and “regular” cigarettes in the pooled population of a multicenter study conducted in Brazil, Poland, China and Mexico.

Methods: Data from smoking behaviors and salivary cotinine were collected following a standard protocol, although sample design was different by country. Linear regression model was used to describe the change in cotinine concentration per cigarette smoked, adjusting for age, BMI, and country of residence and to test interaction between cigarettes smoked in the last 24 hours, type of cigarette and some selected variables.

Results: For the total population, compared to smokers of "regular" cigarettes a greater percentage of "light" cigarette smokers are females (P < 0.001). There is no difference regarding age, BMI and number of cigarette smoked in the past 24 hours. Among women smoking up to 20 cigarettes, no difference was observed in the increase of salivary cotinine levels per cigarette smoked, in both crude or adjusted model. For males, a small difference was observed in the adjusted model. The three way interactions between number of cigarettes smoked in the last 24 hours, type of cigarettes and selected variables – BMI, gender, depth of inhaling, frequency of inhaling and time to smoke the first cigarette after waking up wasn't significant.